Commentaries

2023

  1. Kozue Okamura, Sara Badr, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】A hybrid model of cell cultivation processes in monoclonal antibody production"
    Pharm Tech Japan, 39, 467–471 (2023)
  2. Keita Hirono, Isuru A. Udugama, Yusuke Hayashi, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】A dynamic and probabilistic design space determination method for mesenchymal stem cells"
    Pharm Tech Japan, 39, 39–44 (2023)

2022

  1. Eri Amasawa, Badr Sara, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Sustainability assessment of monoclonal antibody production and its application to design"
    Pharm Tech Japan, 38, 2049–2053 (2022)
  2. Eri Amasawa, Badr Sara, Hirokazu Sugiyama
    "モノクローナル抗体製造から医薬品のサステイナビリティを考える"
    Pharm Stage, 22, 44–55 (2022)
  3. Kensaku Matsunami, Hirokazu Sugiyama
    "Continuous Manufacturing of Solid Drug Products — from Process Systems Engineering Perspectives"
    Journal of the Society of Powder Technology, Japan, 59, 388–393 (2022)
  4. Kozue Okamura, Sara Badr, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Simulation model of cell cultivation process in biopharmaceutical manufacturing and its application to design"
    Pharm Tech Japan, 38, 1625–1629 (2022)
  5. 加納 学, 北川 尚美, 下山 裕介, 杉山 弘和, 高見 誠一, 田中 茂穂, 林 潤一郎, 藤岡 惠子, 藤岡 沙都子, 堀河 俊英, 松田 圭悟
    "VISION2023のレビュー"
    化学工学会誌, 86, 291–300 (2022)
  6. Yusuke Hayashi, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Hybrid-model-based design of fill-freeze-thaw processes for human induced pluripotent stem cells considering productivity and quality"
    Pharm Tech Japan, 38, 585–588 (2022)

2021

  1. Hirokazu Sugiyama, Kensaku Matsunami
    "プロセスシステム工学から見た連続生産"
    化学工学会誌, 85, 615–618 (2021)
  2. Kensaku Matsunami
    "Analysis of the effects of process parameters on start-up operation in continuous wet granulation"
    Pharm Tech Japan, 37, 1337–1338 (2021)
  3. Yusuke Hayashi, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells"
    Pharm Tech Japan, 37, 255–259 (2021)
  4. Hirokazu Sugiyama, Kensaku Matsunami
    "固形剤製造プロセスの経済性評価シミュレーションとツール実装"
    化学装置 最新号, 2021年1月号, 57–62 (2021)

2020

  1. Keisho Yabuta, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Integrated design of H2O2 decontamination processes and scheduling in sterile drug product manufacturing"
    Pharm Tech Japan, 36, 2421–2426 (2020)
  2. Kensaku Matsunami, Hirokazu Sugiyama
    "Simulation tool for the design of solid drug product manufacturing processes"
    Pharm Tech Japan, 36, 1257–1262 (2020)
  3. Masahiro Yamada, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Lot-Size Determination in Pharmaceutical Injectable Manufacturing based on Economic Evaluation"
    Pharm Tech Japan, 36, 871–875 (2020)
  4. Kozue Okamura, Kensaku Matsunami, Haruku Shirahata, Hirokazu Sugiyama
    "Conference report: 2019 American Institute of Chemical Engineers Annual Meeting"
    Pharm Tech Japan, 36, 149–150 (2020)

2019

  1. Hirokazu Sugiyama
    "Pharma PSE Research at The University of Tokyo"
    PD2M Newsletter, 2 (2019)
  2. Yusuke Hayashi, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Slow Freezing Process Design for Human Induced luripotent Stem Cells by Modeling Intracontainer Variation"
    Pharm Tech Japan, 35, 2965–2968 (2019)
  3. Haruku Shirahata, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】Online decision-support tool "TECHoice" for the equipment technology choice in sterile filling processes of biopharmaceuticals"
    Pharm Tech Japan, 35, 2605–2610 (2019)
  4. Kensaku Matsunami, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】 A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide"
    Pharm Tech Japan, 35, 1533–1537 (2019)
  5. Haruku Shirahata, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】 Multiobjective decision-support tools for the choice between single-use and multi-use technologies in sterile filling of biopharmaceuticals"
    Pharm Tech Japan, 35, 377–383 (2019)

2018

  1. Masahiro Yamada, Yusuke Hayashi, Keisho Yabuta, Hirokazu Sugiyama
    "Conference report -50th Autumn Meeting, Society of Chemical Engineers, Japan"
    Pharm Tech Japan, 34, 3209–3210 (2018)
  2. Keisho Yabuta, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】 Design-oriented regression models for H2O2 decontamination processes in sterile drug product manufacturing considering rapidity and sterility"
    Pharm Tech Japan, 34, 2941–2946 (2018)
  3. 杉山 弘和
    "統合化工学"
    化学工学, 82, 574–575 (2018)
  4. Hirokazu Sugiyama, Kensaku Matsunami
    "Continuous manufacturing of drug products from the viewpoint of decision making"
    Pharm Tech Japan, 34, 2261–2265 (2018)
  5. Keisho Yabuta, Hirokazu Sugiyama
    "【Pharma PSE Spotlight】 Process model for enhancing yield in sterile drug product manufacturing"
    Pharm Tech Japan, 34, 1329–1334 (2018)
  6. Gioele Casola
    "創薬・創剤人　リアルデータを基にしたアルゴリズムで工程改善　Gioele Casola氏"
    Pharm Tech Japan, 34, 822–823 (2018)
  7. Hirokazu Sugiyama
    "【Pharma PSE Spotlight】 Multiobjective design of excipients use processes in parenterals manufacturing"
    Pharm Tech Japan, 34, 300–304 (2018)

2017

  1. Keisho Yabuta, Hirokazu Sugiyama, Koji Kawasaki
    "Engineering research approaches for hydrogen peroxide decontamination processes"
    Sinto Technical Report, 35, 32–37 (2017)
  2. Hirokazu Sugiyama
    "【Pharma PSE Spotlight】 Introduction of Pharma PSE COP in ISPE Japan"
    Pharm Tech Japan, 33, 2911–2916 (2017)
  3. 杉山 弘和
    "統合化工学"
    化学工学, 81, 549–550 (2017)
  4. Kensaku Matsunami, Hirokazu Sugiyama
    "Process systems engineering research on continuous manufacturing" (Written in Japanese)
    Pharm Tech Japan, 33, 2619–2625 (2017)
  5. 白畑 春来, 杉山 弘和
    "Pharma PSE Spotlight 第２回： 注射剤製造におけるシングルユース・マルチユース技術の選択支援手法"
    Pharm Tech Japan, 33, 1529–1535 (2017)
  6. 杉山 弘和, 野田 賢
    "プロセスシステム工学アジア国際会議2016 (PSE Asia 2016) 開催報告"
    化学工学, 81, 275–276 (2017)
  7. Hirokazu Sugiyama, Masaaki Ito
    "【Pharma PSE Spotlight】 Planning method for reducing product losses in manufacturing sterile drug products" (Written in Japanese)
    Pharm Tech Japan, 33, 975-979 (2017)

2016

  1. 杉山 弘和
    "統合化工学"
    化学工学, 80, 640–641 (2016)
  2. 杉山 弘和
    "製薬プロセスシステム工学Pharma PSEの開拓"
    Pharm Tech Japan, 32, 2421–2426 (2016)
  3. 杉山 弘和
    "医薬品製造を対象とするプロセスシステム工学の最新動向"
    化学工学, 80, 450 (2016)
  4. 杉山 弘和
    "医薬品製造を対象とするモデル化・シミュレーション・最適化研究"
    クリーンテクノロジー, 26, 65–68 (2016)

2015

  1. 杉山 弘和
    "医薬品製造プロセスの多目的設計"
    化学工業, 66, 952–958 (2015)
  2. 杉山 弘和
    "医薬品製造を対象とする新しいプロセスシステム工学「Pharma PSE」"
    化学工学会バイオ部会ニュースレター, 40, 3–6 (2015)
  3. 杉山 弘和
    "統合化工学"
    化学工学, 79, 765 (2015)
  4. 近藤 康之, 福島 康裕, 村上 進亮, 岡島 敬一, 杉山 弘和, 林 清忠, 松八重 一代, 原 美永子, 松野 泰也, 垣澤 英樹, 本下 晶晴, 中嶌 道靖, 中島 謙一, 伊坪 徳宏, 重富 陽介
    "エコバランス2014国際会議開催報告"
    日本LCA学会誌, 11, 198–206 (2015)

2014

  1. 杉山 弘和
    "統合化工学"
    化学工学, 78, 699–700 (2014)
  2. 杉山 弘和
    "優れた医薬品製造プロセスの実現にむけた工学研究のアプローチ"
    薬剤学, 74, 305–311 (2014)
  3. 杉山 弘和
    "スイスの製薬会社ロシュに勤務して"
    化学工学, 78, 347–348 (2014)

2013

  1. 杉山 弘和
    "統合化工学"
    化学工学, 77, 715–716 (2013)
  2. 杉山 弘和
    "スイス・ロシュ 注射剤製造の現場から"
    薬剤学, 73, 86–89 (2013)